Mesa City was the residence of Muggshot and his goons before his subsequent arrest. The episode, Sunset Snake Eyes, takes place here. Mesa City was once a bustling American boomtown located in the Utah desert. Muggshot scared off its citizens and populated it with casinos and hotels (initially making it his own turf during the events of Sly Cooper and the Thievius Raccoonus). Muggshot's office was located within his largest casino's tallest point, and seven keys were required in order to open it. The city was restored to normal once Muggshot was defeated by Sly and arrested by Carmelita.
Mesa City is mostly noticeable by its desert-like terrain. Off the steep, rigid cliffs the desert expanse continues and a narrow river is visible. Most of the buildings within the city have been abandoned due to Muggshot's reign. The main citizens of the city were replaced by Gamblers, Mobsters, and of course, Muggshot himself. The buildings and roads have fallen into disrepair and the bridges are mostly broken, with train cars placed over them to advance from place to place. The only buildings within the city that are not abandoned are Muggshot's own casinos. After Muggshot's defeat and arrest, the land was re-populated by the exiled locals.
Sly infiltrates Mesa City. He finds it odd that it is deserted, but soon discovers that the reason why the population left is because Muggshot scared them all off. Sly battles some of Muggshot's goons, including Brutes, Watch Dogs and Convicts. Once he finds the Treasure Key, he moves on to the next level.
Sly enters the main hub level of Sunset Snake Eyes. Here, he discovers that Muggshot resides inside the giant fire hydrant located on top of the largest casino in Mesa City. He then moves on to the next mission.
Murray is challenged to a race by Muggshot's goons, and the big prize is a treasure key. Murray must beat the other racers in order for Sly to continue.
One of the few buildings still populated within Mesa City, the Boneyard Casino is falling apart, and filling with water. Sly must recover the treasure key and avoid the mobsters in order to continue.
Murray is trying to retrieve one of the treasure keys, but he needs covering fire. Sly must use the blasting station in order to protect Murray from Muggshot's goons.
Sly meets Carmelita Fox, who tries to arrest him. Sly must evade her and retrieve the treasure key before he ends up fried.
Sly must retrieve one of the two last treasure keys, but this time he needs the help of a wrecking ball to get to it. Once he collects the key, he moves on to the next level.
Sly tries to recover the last of Muggshot's treasure keys, but he needs to be careful not to fall from the tall buildings he's now climbing. Once he collects the final key, he's ready to face Muggshot.
Finally, Sly finds himself face-to-face with the Fiendish Five's enforcer, Muggshot. The dastardly bulldog is not too keen on letting Sly take the pages of the Thievius Raccoonus without a fight. Sly must finish Muggshot off to reclaim what's his.