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Cobra mutants were enemy guards faced by Murray on Kaine Island. They served as Dr. M's rooftop guards.


These mutants had cobra heads, tiger arms and frog feet. They wore brown vests with a dark gray belt around their necks, and their pants were also brown. Their weapon of choice was their mouths; they could drop small bombs, or do a similar attack of Octavio where they would shoot red waves of energy.[1]


  • These guards have similar animations to the Chinese pig guards. This can be seen in their defeat animation, falling, dizzy and counterattack animation.
  • These guards take three hits to defeat with Murray, only shared with the Geese and the Alligator mutant guards.
  • These are one of the few guards in the series Sly Cooper never encounters himself.